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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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SIRPB1 / CD172b
signal-regulatory protein beta 1
SIRPB1 / CD172b is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | signal-regulatory protein beta 1 |
| Synonyms: | SIRPB1, CD172b, SIRP-BETA-1, CD172b antigen, SIRP-beta-1 isoform 3 |
| Target Sequences: | NM_006065 NP_006056.2 O00241 |
Publications (1)
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