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SIPR3 / EDG3 / S1P3
sphingosine-1-phosphate receptor 3
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
| Gene Name: | sphingosine-1-phosphate receptor 3 |
| Family/Subfamily: | GPCR , Lysophospholipid/Lysosphingolipid |
| Synonyms: | S1PR3, EDG-3, EDG3, LPB3, S1P receptor EDG3, S1P3, S1P receptor Edg-3, S1P receptor 3 |
| Target Sequences: | NM_005226 NP_005217.2 Q99500 |
Publications (3)
1
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions. Ruben Van Doorn, Jack Van Horssen, Dennis Verzijl, Maarten Witte, Eric Ronken, Bert Van Het Hof, Kim Lakeman, Christine D. Dijkstra, Paul Van Der Valk, Arie Reijerkerk, Astrid E. Alewijnse, Stephan L. M. Peters, Helga E. De Vries. Glia. 2010 58:1465-76. (ICC, IHC-Fr; Human, Hamster)
[Full Text Article]
[PubMed:20648639]
Related Antibodies: LS-B2155.
2
Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Gril B, Paranjape AN, Woditschka S, Hua E, Dolan EL, Hanson J, Wu X, Kloc W, Izycka-Swieszewska E, Duchnowska R, Peksa R, Biernat W, Jassem J, Nayyar N, Brastianos PK, Hall OM, Peer CJ, Figg WD, Pauly GT, Robinson C, Difilippantonio S, Bialecki E, Metellus P, Schneider JP, Steeg PS. Nature communications. 2018 July;9:2705. (Human)
[Full Text Article]
[PubMed:30006619]
[PMC:PMC6045677]
Related Antibodies: LS-B2155.
3
Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells. van Hooren KW, Spijkers LJ, van Breevoort D, Fernandez-Borja M, Bierings R, van Buul JD, Alewijnse AE, Peters SL, Voorberg J. PloS one. 2014 9:e91346. [Full Text Article]
[PubMed:24632890]
[PMC:PMC3954688]
Related Antibodies: LS-B2155.
☰ Filters
Products
ELISA Kits
(8)
Type
Competitive EIA
(1)
Custom
(1)
Sandwich
(6)
Target
SIPR3 / EDG3 / S1P3
(8)
Reactivity
Human
(3)
Mouse
(4)
Rat
(1)
Format
96-Well Microplate
(1)
96-Well Strip Plate
(7)
Publications
No
(8)
Sample Type
Cell Lysates
(3)
Plasma
(4)
Serum
(4)
Tissue Homogenates
(5)
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
Competitive EIA
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$893
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Mouse
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
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