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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIPA1

signal-induced proliferation-associated 1

Sipa 1 (signal-induced proliferation associated gene 1) is a mitogen-induced GTPase activating protein. It exhibits specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. Sipa1 may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. Sipa 1 has been found in the nucleus, cytoplasm and perinuclear regions, but most in the perinuclear membranous region. The same isoform is encoded by two splice variants.

Gene Name: signal-induced proliferation-associated 1
Synonyms: SIPA1, Sipa-1, SPA1, p130 SPA-1
Target Sequences: NM_006747 NP_006738.3 Q96FS4

Filtered By: None
Target
SIPA1 (28)
Reactivity
Human (27)
Mouse (4)
Rat (1)
Chimpanzee (3)
Gibbon (3)
Hamster (1)
Monkey (6)
Application
IHC (5)
IHC-P (3)
WB (22)
ELISA (13)
ICC (1)
IF (2)
IP (3)
Peptide-ELISA (1)
Host
rabbit (24)
mouse (2)
goat (1)
rat (1)
Isotype
IgG (17)
IgG1,k (2)
IgG2a,k (1)
Clonality
monoclonal mc (3)
polyclonal pc (25)
Clone
2-22-9 (1)
2B4 (1)
331-9 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (16)
Epitope
aa942-970 (8)
aa863-912 (4)
N-Terminus (2)
aa1030-1042 (1)
aa992-1042 (1)
Publications
No (28)
Showing 1-25 of 28 results

SIPA1 Antibody (clone 331-9) IHC-plus™ LS-B12655
Mouse Monoclonal [clone 331-9] (IgG1,k) to Human SIPA1
Human
ICC IHC IHC-P IP WB
Unconjugated
50µg 1mg/ml  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

SIPA1 Antibody (N-Terminus) IHC-plus™ LS-B10609
Rabbit Polyclonal to Mouse SIPA1
Mouse, Rat, Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $425.00
Anti-SIPA1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SIPA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-SIPA1 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SIPA1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

SIPA1 Antibody LS-C671456
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA IF IHC IHC-P WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human lymph node tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human tonsil tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human lymph node tissue at a dilution of 1:100
Immunohistochemistry image of paraffin-embedded human tonsil tissue at a dilution of 1:100

SIPA1 Antibody (N-Terminus) LS-C144471
Rabbit Polyclonal (IgG) to Human SIPA1
Human
IF WB
Unconjugated
100µg  $365.00
Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 ug/ml.
Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 ug/ml.
Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 ug/ml.
Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 ug/ml.

SIPA1 Antibody LS-C402795
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human lung cancer using SIPA1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human lung cancer using SIPA1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human lung cancer using SIPA1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human lung cancer using SIPA1 Polyclonal Antibody at dilution of 1:30.

SIPA1 Antibody LS-C406036
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human cervical cancer using SIPA1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human cervical cancer using SIPA1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human cervical cancer using SIPA1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human cervical cancer using SIPA1 Polyclonal Antibody at dilution of 1:40.

SIPA1 Antibody (aa942-970) LS-C325122
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
Unconjugated
200µl  $530.00

SIPA1 Antibody (aa942-970, Biotin) LS-C269456
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
Biotin Conjugated
200µl  $680.00

SIPA1 Antibody (aa942-970, FITC) LS-C269457
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
FITC Conjugated
200µl  $680.00

SIPA1 Antibody (aa942-970, AP) LS-C269454
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
AP Conjugated
200µl  $680.00

SIPA1 Antibody (aa942-970, PE) LS-C269459
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
PE Conjugated
200µl  $680.00

SIPA1 Antibody (aa942-970, Azide-free, HRP) LS-C269458
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
HRP Conjugated, Azide-free
200µl  $680.00

SIPA1 Antibody (aa942-970, APC) LS-C269455
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
APC Conjugated
200µl  $680.00

SIPA1 Antibody (clone 2-22-9) LS-C179500
Rat Monoclonal [clone 2-22-9] (IgG2a,k) to Mouse SIPA1
Mouse, Hamster
IP WB
Unconjugated
100µg 1mg/ml  $335.00
Western blot Image
Western blot Image

SIPA1 Antibody LS-C752946
Rabbit Polyclonal (IgG) to Human SIPA1
Human
ELISA WB
Unconjugated
100µg  $355.00

SIPA1 Antibody (aa992-1042) LS-C288785
Rabbit Polyclonal (IgG) to Human SIPA1
Mouse, Human, Monkey
IP WB
Unconjugated
100µl 1mg/ml  $395.00

SIPA1 Antibody (clone 2B4) LS-C198199
Mouse Monoclonal [clone 2B4] (IgG1,k) to Human SIPA1
Human
ELISA
Unconjugated
200µl  $355.00

SIPA1 Antibody (aa1030-1042) LS-C55520
Goat Polyclonal to Human SIPA1
Human, Monkey
Peptide-ELISA WB
Unconjugated
100µg  $405.00
Antibody staining (1 ug/ml) of Human EBV-immortalized lymphoblastoid lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
Antibody staining (1 ug/ml) of Human EBV-immortalized lymphoblastoid lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

SIPA1 Antibody (aa863-912) LS-C112258
Rabbit Polyclonal to Human SIPA1
Human, Monkey
WB
Unconjugated
50µg  $365.00
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SIPA1 Antibody (aa863-912, HRP) LS-C465476
Rabbit Polyclonal to Human SIPA1
Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SIPA1 Antibody (aa863-912, Biotin) LS-C465474
Rabbit Polyclonal to Human SIPA1
Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SIPA1 Antibody (aa863-912, FITC) LS-C465475
Rabbit Polyclonal to Human SIPA1
Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl 1mg/ml  $385.00
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
SIPA1 antibody Western blot of HT1080 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SIPA1 Antibody (aa942-970) LS-C161099
Rabbit Polyclonal to Human SIPA1
Human
WB
Unconjugated
400µl  $305.00
SIPA1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The SIPA1 antibody detected the SIPA1 protein (arrow).
SIPA1 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The SIPA1 antibody detected the SIPA1 protein (arrow).

SIPA1 Antibody LS-C668104
Rabbit Polyclonal to Human SIPA1
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image
Western blot Image

SIPA1 Antibody LS-C747402
Rabbit Polyclonal (IgG) to Human SIPA1
Mouse, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of various cell lines, using SIPA1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of various cell lines, using SIPA1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Showing 1-25 of 28 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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