SIP1

gem (nuclear organelle) associated protein 2

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

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Products

Antibodies (29)

Type

Primary (29)

Target

SIP1 (29)

Reactivity

Human (28)

Mouse (14)

Rat (12)

Bat (3)

Bovine (6)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (3)

Hamster (3)

Horse (6)

Monkey (6)

Pig (6)

Rabbit (3)

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Application

IHC (9)

IHC-P (1)

WB (26)

ELISA (6)

ICC (3)

IF (5)

IP (2)

Peptide-ELISA (1)

Host

rabbit (20)

mouse (9)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1 (9)

Clonality

monoclonal mc (9)

polyclonal pc (20)

Clone

2E17 (1)

OTI4A2 (2)

OTI4B3 (2)

OTI4C11 (2)

OTI6G4 (2)

Format

Biotin Conjugated (2)

Carrier-free (4)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (23)

Epitope

C-Terminus (4)

aa35-84 (4)

Internal (1)

aa25-75 (1)

aa429-654 (1)

Publications

No (29)

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IHC-plus™ SIP1 Antibody LS-B5290

(4.0) Rating

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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SIP1 Antibody LS-C332352

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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SIP1 Antibody (clone 2E17) LS-C82217

Antibody:

SIP1 Mouse anti-Human Monoclonal (2E17) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$482

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SIP1 Antibody (clone OTI4B3) LS-C794513

Antibody:

SIP1 Mouse anti-Human Monoclonal (OTI4B3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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SIP1 Antibody (clone OTI4B3, Carrier-free) LS-C791764

Antibody:

SIP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4B3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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SIP1 Antibody (clone OTI4C11) LS-C794519

Antibody:

SIP1 Mouse anti-Human Monoclonal (OTI4C11) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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SIP1 Antibody (clone OTI4C11, Carrier-free) LS-C791768

Antibody:

SIP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4C11) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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SIP1 Antibody LS-C806542

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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SIP1 Antibody (aa429-654) LS-C311911

Antibody:

SIP1 Rabbit anti-Human Polyclonal (aa429-654) Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$450

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SIP1 Antibody LS-C341535

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

SIP1 Antibody LS-C405805

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

SIP1 Antibody LS-C402545

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

SIP1 Antibody LS-C660594

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SIP1 Antibody LS-C781476

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

SIP1 Antibody (aa25-75) LS-C762337

Antibody:

SIP1 Rabbit anti-Human Polyclonal (aa25-75) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

SIP1 Antibody (aa35-84) LS-C135096

Antibody:

SIP1 Rabbit anti-Mouse Polyclonal (aa35-84) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SIP1 Antibody (aa35-84, HRP) LS-C439674

Antibody:

SIP1 Rabbit anti-Mouse Polyclonal (aa35-84) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SIP1 Antibody (aa35-84, Biotin) LS-C440006

Antibody:

SIP1 Rabbit anti-Mouse Polyclonal (aa35-84) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

SIP1 Antibody (clone OTI6G4) LS-C794558

Antibody:

SIP1 Mouse anti-Human Monoclonal (OTI6G4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

SIP1 Antibody (clone OTI6G4, Carrier-free) LS-C791790

Antibody:

SIP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6G4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SIP1 Antibody (clone OTI4A2) LS-C794555

Antibody:

SIP1 Mouse anti-Human Monoclonal (OTI4A2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

SIP1 Antibody (clone OTI4A2, Carrier-free) LS-C791791

Antibody:

SIP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4A2) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

SIP1 Antibody LS-C341050

Antibody:

SIP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

SIP1 Antibody (C-Terminus) LS-C101831

Antibody:

SIP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SIP1 Antibody (Internal) LS-C353791

Antibody:

SIP1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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