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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SIP / TP53INP1

tumor protein p53 inducible nuclear protein 1

Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.

Gene Name: tumor protein p53 inducible nuclear protein 1
Family/Subfamily: Apoptosis
Synonyms: TP53INP1, p53DINP1, SIP, Teap, TP53DINP1, TP53INP1A, p53-inducible p53DINP1, Stress-induced protein, TP53INP1B
Target Sequences: NM_033285 NP_150601.1 Q96A56

Filtered by: None
Target
SIP / TP53INP1 (46)
Reactivity
Human (46)
Mouse (21)
Rat (16)
Dog (4)
Monkey (2)
Application
IHC (30)
IHC-P (6)
WB (41)
ELISA (25)
IF (4)
IP (1)
Peptide-ELISA (2)
Host
rabbit (46)
Isotype
IgG (35)
Clonality
polyclonal pc (46)
Format
AP Conjugated (3)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (23)
Epitope
aa181-210 (8)
aa36-64 (8)
C-Terminus (5)
N-Terminus (2)
aa1-14 (2)
140-220 aa, C-terminal (1)
aa144-193 (1)
aa171-220 (1)
Publications
No (45)
Yes (1)
Showing 1-25 of 46 results

IHC-plus™ SIP / TP53INP1 Antibody LS-B185
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-TP53INP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of p53DINP1 in human liver tissue with p53DINP1 antibody at 5 µg/ml. Green: p53DINP1 antibody  Red: Phylloidin staining Blue: DAPI staining

SIP / TP53INP1 Antibody (N-Terminus) LS-C48323
Publications (1)
Publications (1)
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
IHC, WB
Unconjugated
30µg  $245.00; 100µg 200µl  $415.00

SIP / TP53INP1 Antibody LS-C770
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Rat, Human
WB
Unconjugated
200µl  $335.00
Western blot of p53DINP1 expression in mouse spleen using antibody at 1:5000 dilution.

SIP / TP53INP1 Antibody (140-220 aa, C-terminal) LS-C386470
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of TP53INP1 antibody

SIP / TP53INP1 Antibody (aa181-210) LS-C160126
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
TP53INP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
TP53INP1 Antibody western blot of mouse spleen tissue lysates (35 ug/lane). The TP53INP1 antibody detected the TP53INP1 protein (arrow).

IHC-plus™ SIP / TP53INP1 Antibody LS-B15426
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
60µl  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Immunohistochemistry of paraffin-embedded Human brain using TP53INP1 Polyclonal Antibody at dilution of 1:50.

SIP / TP53INP1 Antibody LS-C501233
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IF, IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human liver cancer using TP53INP1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using TP53INP1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

SIP / TP53INP1 Antibody LS-C661179
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IF, IHC
Unconjugated
100µg  $435.00

SIP / TP53INP1 Antibody (C-Terminus) LS-C353618
Rabbit Polyclonal to Human SIP / TP53INP1
Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of TP53INP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of TP53INP1 expression in HeLa (A); HepG2 (B) whole cell lysates.

SIP / TP53INP1 Antibody (aa36-64) LS-C160127
Rabbit Polyclonal to Human SIP / TP53INP1
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
TP53INP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
TP53INP1 Antibody western blot of SK-BR-3 cell line lysates (35 ug/lane). The TP53INP1 antibody detected the TP53INP1 protein (arrow).

SIP / TP53INP1 Antibody (aa181-210) LS-C325878
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

SIP / TP53INP1 Antibody (aa181-210, Biotin) LS-C242012
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa181-210, FITC) LS-C242013
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa181-210, AP) LS-C242010
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa181-210, APC) LS-C242011
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa181-210, PE) LS-C242014
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa36-64) LS-C325880
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

SIP / TP53INP1 Antibody (aa36-64, Biotin) LS-C242016
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa36-64, FITC) LS-C242018
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa36-64, AP) LS-C242015
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa36-64, APC) LS-C242017
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody (aa36-64, PE) LS-C242022
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

SIP / TP53INP1 Antibody LS-C178474
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg  $275.00
Western blot Image

SIP / TP53INP1 Antibody LS-C807341
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

SIP / TP53INP1 Antibody (N-Terminus) LS-C178674
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg  $275.00
Immunohistochemistry Image
Western blot Image
Showing 1-25 of 46 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).