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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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SIP / TP53INP1

tumor protein p53 inducible nuclear protein 1

Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.

Gene Name: tumor protein p53 inducible nuclear protein 1
Family/Subfamily: Apoptosis
Synonyms: TP53INP1, p53DINP1, SIP, Teap, TP53DINP1, TP53INP1A, p53-inducible p53DINP1, Stress-induced protein, TP53INP1B
Target Sequences: NM_033285 NP_150601.1 Q96A56


SIP / TP53INP1 Antibody - Anti-TP53INP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
SIP / TP53INP1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, IHC-P, WB
Unconjugated
60µl   $425.00
Select
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
IHC, WB
Unconjugated
30µg   0.5mg/ml   $245.00; 100µg   0.5mg/ml   $415.00
SIP / TP53INP1 Antibody - Western blot of p53DINP1 expression in mouse spleen using antibody at 1:5000 dilution.
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Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Rat, Human
WB
Unconjugated
200µl   $335.00
SIP / TP53INP1 Antibody - Western blot of TP53INP1 antibody
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Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
SIP / TP53INP1 Antibody - TP53INP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
SIP / TP53INP1 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using TP53INP1 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IF, IHC
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IF, IHC
Unconjugated
100µg   $435.00
SIP / TP53INP1 Antibody - Immunohistochemical analysis of TP53INP1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human SIP / TP53INP1
Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
100µl   1mg/ml   $245.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
SIP / TP53INP1 Antibody - TP53INP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
Rabbit Polyclonal to Human SIP / TP53INP1
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
SIP / TP53INP1 Antibody
Select
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
SIP / TP53INP1 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human SIP / TP53INP1
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
SIP / TP53INP1 Antibody
Select
Rabbit Polyclonal to Human SIP / TP53INP1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
Viewing 1-25 of 47 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).