SIN3A

SIN3 transcription regulator family member A

Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.

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Proteins (2)

Type

Recombinant (2)

Target

SIN3A (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human SIN3A Protein (Recombinant GST) (Full Length) - LS-G33037

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

43.5 kDa

Price:

2 µg/$439

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Human SIN3A Protein (Recombinant GST, N-terminus) (aa1-99) - LS-G62116

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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