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SIKE1

suppressor of IKBKE 1

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.

Gene Name: suppressor of IKBKE 1
Synonyms: SIKE1, RP5-1000E10.4, SIKE, Suppressor of IKK epsilon, Suppressor of IKBKE 1, Suppressor of IKK-epsilon
Target Sequences: NM_025073 NP_079349.2 Q9BRV8

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SIKE1 (4)
No (4)
His (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Purified (1)
SIKE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23.5 kDa
20 µg/$150
SIKE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.5 kDa
100 µg/$494
SIKE1 Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
SIKE1 Protein - Purified recombinant protein SIKE1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.5 kDa
20 µg/$1,107
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).