SIGLEC8

sialic acid binding Ig-like lectin 8

Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

SIGLEC8 (9)

Publications

No (9)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST, N-terminus (1)

His-GST-S (1)

Mouse IgG Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human (4)

Wheat Germ Extract (1)

Low Endotoxin Level

Low endotoxin level (4)

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Human SIGLEC8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71514

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

20 µg/$1,107

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Human SIGLEC8 Protein (Recombinant GST, N-terminus) (aa18-121) - LS-G62250

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SIGLEC8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89972

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

20 µg/$150

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Human SIGLEC8 Protein (Recombinant His-GST-S) (aa70-336) - LS-G24492

Source:

E. coli

Tag:

His-GST-S

Molecular Weight:

59.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human SIGLEC8 Protein (Recombinant 6His, C-terminus) - LS-G146074

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.6 kDa

Price:

10 µg/$290; 50 µg/$446

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Human SIGLEC8 Protein (Recombinant Fc, C-terminus) - LS-G146088

Source:

Human

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.7 kDa

Price:

10 µg/$290; 50 µg/$446

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Mouse SIGLEC8 Protein (Recombinant 6His, C-terminus) - LS-G146281

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.2 kDa

Price:

10 µg/$341; 50 µg/$641

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Human SIGLEC8 Protein (Recombinant Mouse IgG Fc, C-terminus) - LS-G146485

Source:

Human

Tag:

Mouse IgG Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

64.2 kDa

Price:

10 µg/$290; 50 µg/$446

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SIGLEC8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113933

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.9 kDa

Price:

100 µg/$494

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