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SIGLEC7 / CD328

sialic acid binding Ig-like lectin 7

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).

Gene Name: sialic acid binding Ig-like lectin 7
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: SIGLEC7, AIRM-1, AIRM1, CD328 antigen, CDw328, CD328, D-siglec, QA79, SIGLEC-7, QA79 membrane protein
Target Sequences: NM_014385 NP_055200.1 Q9Y286

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
SIGLEC7 / CD328 (10)
No (10)
6His, C-terminus (1)
GST (1)
GST, N-terminus (1)
His,N-terminus (1)
His-S (2)
Myc-DDK (Flag) (4)
Human (8)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Human (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (1)
SIGLEC7 / CD328 Protein - Recombinant Sialic Acid Binding Ig Like Lectin 7 By SDS-PAGE
Select
E. coli
His,N-terminus
42.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SIGLEC7 / CD328 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.1 kDa
100 µg/$494
SIGLEC7 / CD328 Protein - Recombinant Human Siglec-7/CD328 (C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
37.8 kDa
10 µg/$375; 50 µg/$808
SIGLEC7 / CD328 Protein - 12.5% SDS-PAGE of human SIGLEC7 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
77.11 kDa
2 µg/$439
SIGLEC7 / CD328 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SIGLEC7 / CD328 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51 kDa
20 µg/$150
SIGLEC7 / CD328 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.1 kDa
20 µg/$150
SIGLEC7 / CD328 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51 kDa
100 µg/$494
SIGLEC7 / CD328 Protein - Recombinant Sialic Acid Binding Ig Like Lectin 7 By SDS-PAGE
Select
E. coli
His-S
15.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
His-S
15.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).