SIGLEC12

Sialic acid binding Ig-like lectin 12

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.

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Products

Antibodies (42)

Type

Primary (42)

Target

SIGLEC12 (42)

Reactivity

Human (32)

Mouse (11)

Rat (3)

Bovine (3)

Chimpanzee (6)

Application

IHC (2)

IHC-P (2)

WB (40)

ELISA (1)

Peptide-ELISA (1)

Host

rabbit (41)

goat (1)

Isotype

IgG (15)

Clonality

polyclonal pc (42)

Format

APC (3)

APC Conjugated (3)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (3)

Unconjugated (12)

Epitope

aa22-218 (8)

aa27-141 (8)

aa317-512 (8)

aa110-159 (4)

aa218-267 (4)

aa38-87 (4)

aa464-477 (1)

aa565-595 (1)

Publications

No (42)

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SIGLEC12 Antibody LS-C676490

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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SIGLEC12 Antibody (aa565-595) LS-C161089

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa565-595) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SIGLEC12 Antibody LS-C770612

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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SIGLEC12 Antibody (aa27-141) LS-C296406

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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SIGLEC12 Antibody (aa27-141, HRP) LS-C709305

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557

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SIGLEC12 Antibody (aa27-141, Biotin) LS-C301161

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317

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SIGLEC12 Antibody (aa27-141, FITC) LS-C692151

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676

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SIGLEC12 Antibody (aa27-141, APC) LS-C739522

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

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SIGLEC12 Antibody (aa27-141, Cy3) LS-C700281

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

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SIGLEC12 Antibody (aa27-141, APC, Cy7) LS-C732358

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592

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SIGLEC12 Antibody (aa27-141, PE) LS-C723364

Antibody:

SIGLEC12 Rabbit anti-Mouse Polyclonal (aa27-141) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• Cy3
• APC, Cy7
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • Cy3
  • APC, Cy7
  • PE

Select

SIGLEC12 Antibody (aa218-267) LS-C81530

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa218-267) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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SIGLEC12 Antibody (aa38-87) LS-C81538

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa38-87) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SIGLEC12 Antibody (aa110-159) LS-C81539

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa110-159) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

SIGLEC12 Antibody (aa22-218) LS-C296408

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa22-218) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

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SIGLEC12 Antibody (aa22-218, HRP) LS-C709307

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa22-218) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

Select

SIGLEC12 Antibody (aa22-218, Biotin) LS-C299223

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa22-218) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$313; 200 µl/$357; 500 µl/$503; 1 ml/$576; 2 ml/$788; 5 ml/$1,279

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SIGLEC12 Antibody (aa22-218, APC) LS-C739524

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa22-218) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

Select

SIGLEC12 Antibody (aa22-218, Cy3) LS-C700277

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa22-218) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

• Unconjugated
• HRP
• Biotin
• APC
• Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • Cy3

Select

SIGLEC12 Antibody LS-C668908

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

SIGLEC12 Antibody LS-C410054

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

SIGLEC12 Antibody (aa317-512) LS-C374086

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa317-512) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

SIGLEC12 Antibody (aa317-512, HRP) LS-C709303

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa317-512) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

Select

SIGLEC12 Antibody (aa317-512, APC) LS-C739523

Antibody:

SIGLEC12 Rabbit anti-Human Polyclonal (aa317-512) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$396; 200 µl/$476; 500 µl/$815; 1 ml/$969; 2 ml/$1,240; 5 ml/$2,325

• Unconjugated
• HRP
• APC

• Unconjugated
• HRP
• APC

Select

SIGLEC12 Antibody (aa464-477) LS-C55466

Antibody:

SIGLEC12 Goat anti-Human Polyclonal (aa464-477) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$401

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