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SHMT / SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

SHMT / SHMT2 is the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants.

Gene Name: serine hydroxymethyltransferase 2 (mitochondrial)
Synonyms: SHMT2, GLY A+, GLYA, Hydroxymethyltransferase 2, Serine methylase, Serine aldolase, SHMT, Threonine aldolase, Serine hydroxymethylase
Target Sequences: NM_005412 NP_005403.2 P34897

☰ Filters
Products
Antibodies (37)
Primary (37)
SHMT / SHMT2 (37)
Human (37)
Mouse (12)
Rat (11)
Bat (6)
Bovine (3)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (6)
Monkey (6)
Orangutan (3)
Pig (14)
Rabbit (6)
Xenopus (3)
Zebrafish (3)
IHC (20)
IHC-P (10)
WB (35)
ELISA (2)
ICC (2)
IF (4)
IP (3)
Peptide-ELISA (1)
rabbit (24)
mouse (13)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (4)
IgG2a (4)
IgG2a,k (1)
IgG2b (4)
monoclonal mc (13)
polyclonal pc (24)
5E7 (1)
OTI1C1 (2)
OTI1E12 (2)
OTI1E6 (2)
OTI3B3 (2)
OTI3E9 (2)
OTI5H10 (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Carrier-free (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (24)
aa30-504 (8)
aa401-450 (4)
aa72-121 (4)
aa25-75 (1)
aa454-504 (1)
No (37)
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa401-450) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa401-450) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa401-450) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa401-450) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
SHMT / SHMT2 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SHMT / SHMT2 Antibody - Immunohistochemical analysis of SHMT2 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (OTI1E12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1E12) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (OTI3E9) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3E9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
SHMT / SHMT2 Antibody - Western blot of SHMT / SHMT2 antibody.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa30-504) Antibody
Pig, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (OTI1E6) Antibody
Human
IHC
Unconjugated
100 µl/$434
SHMT / SHMT2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SHMT2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:150)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1E6) Antibody
Human
IHC
Unconjugated, Carrier-free
100 µg/$511
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa72-121) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa72-121) (HRP) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa72-121) (Biotin) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
SHMT / SHMT2 Antibody - SHMT2 antibody SHMT2(serine hydroxymethyltransferase 2 (mitochondrial)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa72-121) (FITC) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
SHMT / SHMT2 Antibody - 1:100 staining human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SHMT / SHMT2 Antibody - Western blot of SHMT2 pAb in extracts from 293T cells.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$391; 100 µl/$489
SHMT / SHMT2 Antibody - SHMT2 monoclonal antibody (M04), clone 5E7. Western Blot analysis of SHMT2 expression in HeLa.
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SHMT / SHMT2 Mouse anti-Human Monoclonal (5E7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SHMT / SHMT2 Antibody - Detection of human SHMT2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SHMT2 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa25-75) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SHMT / SHMT2 Antibody - Detection of human and mouse SHMT2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SHMT2 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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SHMT / SHMT2 Rabbit anti-Human Polyclonal (aa454-504) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SHMT / SHMT2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SHMT2. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SHMT2. (1:2000)
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SHMT / SHMT2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C1) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).