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SH3BP2

SH3-domain binding protein 2

SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: SH3-domain binding protein 2
Synonyms: SH3BP2, Abl-SH3 binding protein 2, 3BP-2, 3BP2, Cherubism, CRPM, RES4-23, SH3 domain-binding protein 2, TNFAIP3 interacting protein 2, CRBM, SH3-domain binding protein 2
Target Sequences: NM_003023 NP_003014.3 P78314

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
SH3BP2 (8)
No (8)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (1)
SH3BP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
SH3BP2 Protein - Recombinant SH3 Domain Binding Protein 2 (SH3BP2) by SDS-PAGE
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E. coli
His, N-Terminal
32.6kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
SH3BP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SH3BP2 Protein - Purified recombinant protein SH3BP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
SH3BP2 Protein - Purified recombinant protein SH3BP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
SH3BP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
SH3BP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
SH3BP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).