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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SH2B2 / APS

SH2B adaptor protein 2

Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.

Gene Name: SH2B adaptor protein 2
Synonyms: SH2B2, APS, SH2B adapter protein 2, SH2B adaptor protein 2
Target Sequences: NM_020979

Filtered By: None
Target
SH2B2 / APS (6)
Reactivity
Human (5)
Mouse (4)
Rat (5)
Hamster (1)
Monkey (1)
Application
IHC (3)
WB (4)
ELISA (4)
Host
rabbit (5)
goat (1)
Isotype
IgG (5)
Clonality
polyclonal pc (6)
Format
Unconjugated (6)
Epitope
Internal (2)
N-Terminus (1)
aa620-632 (1)
Publications
No (6)
Showing 1-6 of 6 results

SH2B2 / APS Antibody (Internal) LS-C153543
Rabbit Polyclonal to Mouse SH2B2 / APS
Mouse, Rat
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $315.00

SH2B2 / APS Antibody LS-C406227
Rabbit Polyclonal (IgG) to Human SH2B2 / APS
Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using SH2B2 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human gastric cancer using SH2B2 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human gastric cancer using SH2B2 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of Human gastric cancer using SH2B2 Polyclonal Antibody at dilution of 1:15.

SH2B2 / APS Antibody LS-C402993
Rabbit Polyclonal (IgG) to Human SH2B2 / APS
Rat, Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human esophagus cancer using SH2B2 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human esophagus cancer using SH2B2 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human esophagus cancer using SH2B2 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of Human esophagus cancer using SH2B2 Polyclonal Antibody at dilution of 1:30.

SH2B2 / APS Antibody (Internal) LS-C382075
Rabbit Polyclonal (IgG) to Human SH2B2 / APS
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of APS antibody
Western blot of APS antibody

SH2B2 / APS Antibody (N-Terminus) LS-C35051
Rabbit Polyclonal (IgG) to Human SH2B2 / APS
Mouse, Human
WB
Unconjugated
100µl  $530.00

SH2B2 / APS Antibody (aa620-632) LS-C126877
Goat Polyclonal (IgG) to Human SH2B2 / APS
Mouse, Rat, Hamster, Human, Monkey
WB
Unconjugated
100µg  $710.00
Showing 1-6 of 6 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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