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SGOL2

shugoshin-like 2 (S. pombe)

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation By similarity. Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Gene Name: shugoshin-like 2 (S. pombe)
Synonyms: SGOL2, Shugoshin-like 2 (S. pombe), SGO2, Shugoshin-like 2, Shugoshin-2, TRIPIN
Target Sequences: NP_689737.4 Q562F6

☰ Filters
Products
Antibodies (12)
Primary (12)
SGOL2 (12)
Human (12)
IHC (3)
IHC-P (1)
WB (8)
ELISA (8)
IP (2)
Peptide-ELISA (1)
rabbit (12)
IgG (11)
polyclonal pc (12)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa391-419 (7)
650-730 aa, Internal (1)
aa175-225 (1)
aa681-730 (1)
aa750-800 (1)
No (12)
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SGOL2 Rabbit anti-Human Polyclonal (650-730 aa, Internal) Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
SGOL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
SGOL2 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using SGOL2 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
SGOL2 Rabbit anti-Human Polyclonal (aa681-730) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
SGOL2 Rabbit anti-Human Polyclonal (aa391-419) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SGOL2 Rabbit anti-Human Polyclonal (aa750-800) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SGOL2 Antibody - SGOL2 Antibody western blot of U-937 cell line lysates (35 ug/lane). The SGOL2 antibody detected the SGOL2 protein (arrow).
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SGOL2 Rabbit anti-Human Polyclonal (aa391-419) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
SGOL2 Rabbit anti-Human Polyclonal (aa175-225) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).