SGOL1 / Shugoshin

shugoshin-like 1 (S. pombe)

Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity.

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Products

Proteins (13)

Type

Over-Expression Lysate (10)

Recombinant (3)

Target

SGOL1 / Shugoshin (13)

Publications

No (13)

Tag

GST (1)

Myc-DDK (Flag) (12)

Species

Human (8)

Source

293T Cells (5)

HEK 293 Cells (7)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84560

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64 kDa

Price:

20 µg/$215

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Human SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84561

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.1 kDa

Price:

20 µg/$150

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Human SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84562

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

20 µg/$150

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Human SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84563

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.3 kDa

Price:

20 µg/$150

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Human SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84564

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.3 kDa

Price:

20 µg/$150

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Human SGOL1 / Shugoshin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69408

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.3 kDa

Price:

20 µg/$1,107

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Human SGOL1 / Shugoshin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69409

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.1 kDa

Price:

20 µg/$1,107

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Human SGOL1 / Shugoshin Protein (Recombinant GST) (Full Length) - LS-G36748

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.86 kDa

Price:

2 µg/$439

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SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107292

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.3 kDa

Price:

100 µg/$494

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SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121381

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64 kDa

Price:

100 µg/$710

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SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121382

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.1 kDa

Price:

100 µg/$494

Select

SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121383

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.2 kDa

Price:

100 µg/$494

Select

SGOL1 / Shugoshin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121384

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.3 kDa

Price:

100 µg/$494

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