SGMS1 / TMEM23

sphingomyelin synthase 1

Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

SGMS1 / TMEM23 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human SGMS1 / TMEM23 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82434

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.4 kDa

Price:

20 µg/$150

Select

Human SGMS1 / TMEM23 Protein (Recombinant GST) (Full Length) - LS-G37155

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

71.17 kDa

Price:

10 µg/$479; 25 µg/$670

Select

SGMS1 / TMEM23 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106539

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.4 kDa

Price:

100 µg/$494

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.