SGK3

serum/glucocorticoid regulated kinase family, member 3

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na+ channels: SCNN1A/ENAC and SCN5A, K+ channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca2+ channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na+/dicarboxylate cotransporter: SLC13A2/NADC1, Na+-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na+/H+ exchanger: SLC9A3/NHE3, and the Na+/K+ ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

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Products

Antibodies (50)

Proteins (13)

Type

Over-Expression Lysate (6)

Primary (50)

Recombinant (7)

Target

SGK3 (63)

Reactivity

Human (41)

Mouse (22)

Rat (7)

Bat (4)

Bovine (6)

Chicken (3)

Chimpanzee (3)

Dog (4)

Gibbon (6)

Guinea pig (3)

Hamster (1)

Horse (3)

Monkey (8)

Orangutan (6)

Pig (3)

Rabbit (7)

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Application

IHC (18)

IHC-P (11)

WB (45)

ELISA (17)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (49)

mouse (1)

Product Group

IHCPlus (4)

PathPlus Neuro (1)

Isotype

IgG (17)

IgG2b,k (1)

Clonality

monoclonal mc (2)

polyclonal pc (48)

Clone

2A7 (1)

D30E6 (1)

Format

APC (2)

APC Conjugated (4)

Azide-free (2)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (4)

Unconjugated (20)

Epitope

aa141-368 (8)

aa40-311 (8)

aa1-30 (7)

aa381-409 (7)

C-Terminus (5)

aa107-156 (4)

N-Terminus (2)

Internal (1)

aa1-150 (1)

pThr320 (1)

Publications

No (63)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

His,N-terminus + GST (1)

His-T7 (2)

Myc-DDK (Flag) (7)

Species

Human (9)

Mouse (1)

Source

293T Cells (3)

E. coli (3)

HEK 293 Cells (4)

Insect Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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PathPlus™ SGK3 Antibody (N-Terminus) LS-A7230

Neuroscience

Fast Shipping

(5.0) Rating

Antibody:

SGK3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ SGK3 Antibody (C-Terminus) LS-A7246

Fast Shipping

(4.0) Rating

Antibody:

SGK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Rabbit, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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SGK3 Antibody (phospho-Thr320, clone D30E6) LS-C184122

Antibody:

SGK3 Rabbit anti-Human Monoclonal (pThr320) (D30E6) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$689

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IHC-plus™ SGK3 Antibody (Internal) LS-A7240

Fast Shipping

(4.0) Rating

Antibody:

SGK3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Dog, Rat, Hamster, Bat, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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SGK3 Antibody (aa1-30) LS-C99745

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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SGK3 Antibody LS-C754067

Antibody:

SGK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

SGK3 Antibody (aa107-156) LS-B4684

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa107-156) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

SGK3 Antibody (aa107-156, HRP) LS-C460425

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa107-156) (HRP) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

SGK3 Antibody (aa107-156, Biotin) LS-C460423

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa107-156) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

SGK3 Antibody (aa107-156, FITC) LS-C460424

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa107-156) (FITC) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Dog, Guinea pig, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

SGK3 Antibody (clone 2A7) LS-C133707

Antibody:

SGK3 Mouse anti-Human Monoclonal (2A7) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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IHC-plus™ SGK3 Antibody (N-Terminus) LS-A7238

Fast Shipping

(4.0) Rating

Antibody:

SGK3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

SGK3 Antibody (aa1-30) LS-C325064

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SGK3 Antibody (aa1-30, Biotin) LS-C240687

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa1-30, FITC) LS-C240686

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa1-30, APC) LS-C240685

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa1-30, PE) LS-C240690

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa1-30, Azide-free, HRP) LS-C248137

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

SGK3 Antibody (aa1-150) LS-C378478

Antibody:

SGK3 Rabbit anti-Human Polyclonal (aa1-150) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

SGK3 Antibody (aa381-409) LS-C325063

Antibody:

SGK3 Rabbit anti-Mouse Polyclonal (aa381-409) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

SGK3 Antibody (aa381-409, Biotin) LS-C240682

Antibody:

SGK3 Rabbit anti-Mouse Polyclonal (aa381-409) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa381-409, FITC) LS-C240680

Antibody:

SGK3 Rabbit anti-Mouse Polyclonal (aa381-409) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa381-409, PE) LS-C240683

Antibody:

SGK3 Rabbit anti-Mouse Polyclonal (aa381-409) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

SGK3 Antibody (aa381-409, Azide-free, HRP) LS-C248136

Antibody:

SGK3 Rabbit anti-Mouse Polyclonal (aa381-409) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free

Select

SGK3 Antibody LS-C781509

Antibody:

SGK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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