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SGCZ
sarcoglycan, zeta
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single transmembrane region and a large extra-cellular domain containing a carboxyl-terminal cluster with several conserved cysteine residues. The sarcoglycan complex is part of the dystrophin-associated glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extra-cellular matrix.
| Gene Name: | sarcoglycan, zeta |
| Synonyms: | SGCZ, Zeta-SG, ZSG1, Sarcoglycan, zeta, Zeta-sarcoglycan |
| Target Sequences: | NM_139167 NP_631906.2 Q96LD1 |
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