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SFRP1

secreted frizzled-related protein 1

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Gene Name: secreted frizzled-related protein 1
Synonyms: SFRP1, FrzA, FRP, SARP-2, SARP2, SFRP-1, FRP-1, FRP1
Target Sequences: NM_003012 NP_003003.3 Q8N474

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
SFRP1 (9)
No (9)
GST (1)
His (4)
Myc-DDK (Flag) (2)
Human (6)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
HeLa Cells (1)
Human Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (2)
Biologically active (2)
SFRP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.2 kDa
20 µg/$150
SFRP1 Protein - Recombinant Secreted Frizzled Related Protein 1 By SDS-PAGE
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E. coli
His
18.2 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
SFRP1 Protein - Recombinant Secreted Frizzled Related Protein 1 By SDS-PAGE
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E. coli
His
34.2 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SFRP1 Protein - 12.5% SDS-PAGE of human SFRP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
60.28 kDa
2 µg/$439
SFRP1 Protein - Recombinant Secreted Frizzled Related Protein 1 By SDS-PAGE
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E. coli
His
36.2 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
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None
Biologically active
20 µg/$492
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HeLa Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
5 µg/$268; 20 µg/$349
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
34 kDa
50 µg/$600
SFRP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.2 kDa
100 µg/$494
Viewing 1-9 of 9 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).