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SF3B4

splicing factor 3b, subunit 4, 49kDa

Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Gene Name: splicing factor 3b, subunit 4, 49kDa
Synonyms: SF3B4, AFD1, Hsh49, SAP 49, Spliceosomal protein, SF3b50, SAP49, SF3b49, Splicing factor 3B subunit 4
Target Sequences: NM_005850 NP_005841.1 Q15427

☰ Filters
Antibodies (28)
Proteins (2)
Primary (28)
Recombinant (2)
SF3B4 (30)
Human (28)
Mouse (17)
Rat (16)
Bat (7)
Bovine (9)
Chicken (6)
Chimpanzee (6)
Dog (7)
Gibbon (3)
Guinea pig (6)
Hamster (7)
Horse (7)
Monkey (7)
Pig (8)
Rabbit (7)
Xenopus (7)
Zebrafish (7)
IHC (13)
IHC-P (6)
WB (27)
ELISA (10)
ICC (2)
IF (4)
IP (1)
Peptide-ELISA (3)
rabbit (25)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (23)
IgG2 (1)
IgG2b,k (1)
monoclonal mc (2)
polyclonal pc (26)
3A1 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (17)
aa158-187 (7)
N-Terminus (4)
aa151-200 (4)
30-110 aa, Internal (1)
Internal (1)
aa2-14 (1)
aa374-424 (1)
aa49-98 (1)
No (30)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
SF3B4 Antibody - Anti-SF3B4 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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SF3B4 Mouse anti-Human Monoclonal (3A1) Antibody
Mouse, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SF3B4 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SF3B4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SF3B4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
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SF3B4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
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SF3B4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
SF3B4 Antibody - Western blot of SAP 49 antibody
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SF3B4 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SF3B4 Antibody - Immunofluorescence staining of SF3B4 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human SF3B4 polyclonal antibody (dilution ratio 1:100) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus.
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SF3B4 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
SF3B4 Antibody - Detection of Human and Mouse SF3B4 by Western Blot. Samples: Whole cell lysate from 293T (15 and 50 ug), HeLa (50 ug), Jurkat (50 ug), and mouse NIH3T3 (50 ug) cells. Antibodies: Affinity purified rabbit anti-SF3B4 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.
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SF3B4 Rabbit anti-Human Polyclonal (aa374-424) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
SF3B4 Antibody - Western blot analysis of the lysates from 293 cells using SF3B4 antibody.
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SF3B4 Rabbit anti-Human Polyclonal (aa49-98) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SF3B4 Antibody - SF3B4 antibody ARP40609_T100-NP_005841-SF3B4 (splicing factor 3b, subunit 4, 49kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SF3B4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
SF3B4 Antibody - SF3B4 antibody ARP40609_T100-NP_005841-SF3B4 (splicing factor 3b, subunit 4, 49kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SF3B4 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
SF3B4 Antibody - SF3B4 antibody ARP40609_T100-NP_005841-SF3B4 (splicing factor 3b, subunit 4, 49kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SF3B4 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
SF3B4 Antibody - SF3B4 antibody ARP40609_T100-NP_005841-SF3B4 (splicing factor 3b, subunit 4, 49kDa) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SF3B4 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
SF3B4 Antibody - Immunohistochemical analysis of SAP49 staining in human lung formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SF3B4 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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SF3B4 Mouse anti-Rat Monoclonal (3A1) Antibody
Mouse, Bovine, Rat, Human
IF, WB
Unconjugated
100 µl/$469
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
SF3B4 Rabbit anti-Human Polyclonal (aa158-187) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
SF3B4 Antibody - Antibody staining (0.1 ug/ml) of HeLa lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.
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SF3B4 Goat anti-Human Polyclonal (aa2-14) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Rabbit, Mouse, Dog, Bovine, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
SF3B4 Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SF3B4 Rabbit anti-Human Polyclonal (aa151-200) Antibody
Human
WB
Unconjugated
100 µl/$424
SF3B4 Antibody - SF3B4 Antibody western blot of HeLa cell line lysates (35 ug/lane). The SF3B4 antibody detected the SF3B4 protein (arrow).
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SF3B4 Rabbit anti-Human Polyclonal (aa158-187) Antibody
Human
WB
Unconjugated
400 µl/$393
SF3B4 Antibody - Western blot testing of human 1) placenta, 2) MDA-MB-231, 3) U-2 OS, 4) HL-60, 5) A549, 6) PC-3, 7) ThP-1 and 8) U-87 MG lysate with SF3B4 antibody at 0.5ug/ml. Predicted molecular weight ~44 kDa but routinely observed at ~49 kDa.
Select
SF3B4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$575
Viewing 1-25 of 30 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).