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SF3B2

splicing factor 3b, subunit 2, 145kDa

SF3B2 is subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.

Gene Name: splicing factor 3b, subunit 2, 145kDa
Synonyms: SF3B2, Cus1, SAP 145, SAP145, SF3B145, Splicing factor 3B subunit 2, SF3b150
Target Sequences: BC000401 AAH00401.2 Q13435

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SF3B2 (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
SF3B2 Protein - Purified recombinant protein SF3B2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
100 kDa
20 µg/$1,107
SF3B2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SF3B2 Protein - 12.5% SDS-PAGE of human SF3B2 stained with Coomassie Blue
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Wheat Germ Extract
GST
95.48 kDa
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
100.7 kDa
20 µg/$215
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HEK 293 Cells
Myc-DDK (Flag)
100.7 kDa
100 µg/$710
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).