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SF3A2 / SF3a66

splicing factor 3a, subunit 2, 66kDa

Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Gene Name:	splicing factor 3a, subunit 2, 66kDa
Synonyms:	SF3A2, PRP11, SAP 62, SF3a66, PRPF11, SAP62, Splicing factor 3A subunit 2
Target Sequences:	NM_007165 NP_009096.2 Q15428

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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