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Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
Gene Name: | SERTA domain containing 1 |
Synonyms: | SERTAD1, CDK4-binding protein p34SEI, SEI-1, SERTA domain containing 1, TRIP-Br1, CDK4-binding protein p34SEI1, SEI1 |
Target Sequences: | NM_013376 NP_037508.2 Q9UHV2 |
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