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SERPIND1 / Heparin Cofactor 2

serpin peptidase inhibitor, clade D (heparin cofactor), member 1

Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.

Gene Name: serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Synonyms: SERPIND1, D22S673, HCII, HLS2, HC-II, HC2, Leuserpin 2, LS2, HCF2, Heparin cofactor 2, THPH10, Protease inhibitor leuserpin-2, Serpin D1
Target Sequences: NM_000185 NP_000176.2 P05546

Publications (1)

1
Salivary proteome profiling of oral squamous cell carcinoma in a Hungarian population. Csosz É, Márkus B, Darula Z, Medzihradszky KF, Nemes J, Szabó E, Tozsér J, Kiss C, Márton I. FEBS open bio. 2018 February;8:556-569. [Full Text Article] [PubMed:29632809] [PMC:PMC5881539]

☰ Filters
Products
Proteins (12)
Over-Expression Lysate (2)
Recombinant (10)
SERPIND1 / Heparin Cofactor 2 (12)
No (12)
6His, C-terminus (2)
6His, N-terminus (1)
GST (1)
His (3)
His-GST-S (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (6)
Mouse (4)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Human Cells (3)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (5)
Low endotoxin level (4)
SERPIND1 / Heparin Cofactor 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
56.96 kDa
20 µg/$150
SERPIND1 / Heparin Cofactor 2 Protein
Select
E. coli
6His, N-terminus
65 kDa
10 µg/$265; 50 µg/$315
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
56.4 kDa
50 µg/$854
SERPIND1 / Heparin Cofactor 2 Protein - Recombinant  Heparin Cofactor II By SDS-PAGE
Select
E. coli
His-GST-S
40.0 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
SERPIND1 / Heparin Cofactor 2 Protein - Recombinant Heparin Cofactor II By SDS-PAGE
Select
E. coli
His-T7
29.5 kDa
10 µg/$285; 50 µg/$467; 100 µg/$747; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246
SERPIND1 / Heparin Cofactor 2 Protein - Recombinant Heparin Cofactor II By SDS-PAGE
Select
E. coli
His-T7
28.1 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
SERPIND1 / Heparin Cofactor 2 Protein - 12.5% SDS-PAGE of human SERPIND1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
83.4 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.1 kDa
10 µg/$317; 50 µg/$524
SERPIND1 / Heparin Cofactor 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
56.96 kDa
100 µg/$494
SERPIND1 / Heparin Cofactor 2 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
53.5 kDa
50 µg/$854
Viewing 1-12 of 12 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).