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SERPINB6 / PI-6

serpin peptidase inhibitor, clade B (ovalbumin), member 6

SERPINB6 / PI-6 is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 6
Synonyms: SERPINB6, CAP, Cytoplasmic antiproteinase, DFNB91, Peptidase inhibitor 6, PI-6, PI6, PTI, Serpin B6, MSTP057, Placental thrombin inhibitor, SPI3
Target Sequences: NM_004568 NP_004559.4 P35237

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
SERPINB6 / PI-6 (8)
No (8)
GST (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (3)
TRX, N-terminus (1)
TRX-6His, N-terminus (1)
Human (7)
293T Cells (1)
Baculovirus (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (3)
Select
E. coli
TRX-6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.7kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
SERPINB6 / PI-6 Protein - Purified recombinant protein SERPINB6 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
42.4 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
42.4 kDa
20 µg/$150
SERPINB6 / PI-6 Protein - Recombinant  Placental Thrombin Inhibitor By SDS-PAGE
Select
E. coli
His-T7
46.3 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
SERPINB6 / PI-6 Protein - 12.5% SDS-PAGE of human SERPINB6 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
67.1 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
TRX, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
60.7 kDa
10 µg/$317; 50 µg/$524
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
44.9 kDa
50 µg/$721
SERPINB6 / PI-6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.4 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).