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Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
Gene Name: | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 |
Synonyms: | SERPINA4, KAL, PI4, Kallistatin, KLST, KST, Peptidase inhibitor 4, PI-4, Serpin A4, Kallikrein inhibitor |
Target Sequences: | NM_006215 NP_006206.2 P29622 |
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