SERF1A / SERF1

small EDRK-rich factor 1A (telomeric)

SERF1A / SERF1 is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known; however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product. Alternatively spliced transcripts have been documented but it is unclear whether alternative splicing occurs for both the centromeric and telomeric copies of the gene.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

SERF1A / SERF1 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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SERF1A / SERF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127192

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.2 kDa

Price:

100 µg/$494

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SERF1A / SERF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110539

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.2 kDa

Price:

100 µg/$494

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Human SERF1A / SERF1 Protein (Recombinant GST) (Full Length) - LS-G31096

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human SERF1A / SERF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68885

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.2 kDa

Price:

20 µg/$1,107

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Human SERF1A / SERF1 Protein (Recombinant GST, N-terminus) (aa1-82) - LS-G60676

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SERF1A / SERF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83312

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

12.2 kDa

Price:

20 µg/$150

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Human SERF1A / SERF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83313

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.2 kDa

Price:

20 µg/$150

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