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SEPX1 / Selenoprotein R

methionine sulfoxide reductase B1

Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages.

Gene Name: methionine sulfoxide reductase B1
Synonyms: MSRB1, Selenoprotein R, Selenoprotein X, 1, SELR, SepR, HSPC270, Selenoprotein X, SELX, SEPX1
Target Sequences: NM_016332 NP_057416.1 Q9NZV6

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
SEPX1 / Selenoprotein R (6)
No (6)
GST (1)
GST, N-terminus (1)
His (2)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
SEPX1 / Selenoprotein R Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SEPX1 / Selenoprotein R Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
12.7 kDa
20 µg/$150
SEPX1 / Selenoprotein R Protein - Recombinant Selenoprotein X1 By SDS-PAGE
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E. coli
His
14.3 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
SEPX1 / Selenoprotein R Protein - 12.5% SDS-PAGE of human SEPX1 stained with Coomassie Blue
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Wheat Germ Extract
GST
36.8 kDa
10 µg/$479; 25 µg/$670
SEPX1 / Selenoprotein R Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
SEPX1 / Selenoprotein R Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
12.7 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).