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SEPW1 / Selenoprotein W
selenoprotein W, 1
SEPW1 / Selenoprotein W is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.
| Gene Name: | selenoprotein W, 1 |
| Synonyms: | SEPW1, Selenoprotein W, SelW, Selenoprotein W, 1 |
| Target Sequences: | NM_003009 NP_003000.1 P63302 |
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