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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SENP1

SUMO1/sentrin specific peptidase 1

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1.

Gene Name: SUMO1/sentrin specific peptidase 1
Family/Subfamily: Protease , Cysteine C48
Synonyms: SENP1, Sentrin-specific protease 1, SuPr-2
Target Sequences: NM_014554 NP_055369.1 Q9P0U3

Publications (1)

1
MDM2-ARF complex regulates p53 sumoylation. Chen L, Chen J. Oncogene. 2003 22:5348-57. [PubMed:12917636] Related Antibodies: LS-B3387.

Filtered By: None
Target
SENP1 (47)
Reactivity
Human (39)
Mouse (18)
Rat (5)
Bat (4)
Bovine (5)
Chimpanzee (3)
Dog (6)
Gibbon (3)
Guinea pig (4)
Horse (5)
Monkey (1)
Orangutan (3)
Pig (5)
Rabbit (5)
Application
IHC (22)
IHC-P (8)
WB (43)
Flo (1)
ELISA (30)
IF (1)
IP (3)
Peptide-ELISA (1)
Host
rabbit (46)
mouse (1)
Isotype
IgG (41)
IgG1 (1)
Clonality
monoclonal mc (1)
polyclonal pc (46)
Clone
1D7 (1)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (23)
Epitope
aa262-289 (8)
aa28-59 (8)
aa560-590 (8)
C-Terminus (4)
aa1-50 (2)
1-80 aa, N-terminal (1)
Asp2 (1)
N-Terminus (1)
aa150-200 (1)
aa578-590 (1)
Publications
No (46)
Yes (1)
Showing 1-25 of 47 results

SENP1 Antibody (aa28-59) IHC-plus™ LS-B3387
Publications (1)
Publications (1)
Rabbit Polyclonal to Human SENP1
Human
IHC IHC-P WB
Unconjugated
200µl  $425.00
Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of SENP1 polyclonal antibody in whole HL60 cell lysate: SENP1 (Arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of SENP1 polyclonal antibody in whole HL60 cell lysate: SENP1 (Arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

SENP1 Antibody (aa1-50) IHC-plus™ LS-B7649
Rabbit Polyclonal (IgG) to Human SENP1
Mouse, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from Jurkat cells, using SENP1 Antibody. The lane on the right is blocked with the synthesized peptide.
Anti-SENP1 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot analysis of lysates from Jurkat cells, using SENP1 Antibody. The lane on the right is blocked with the synthesized peptide.

SENP1 Antibody (aa560-590) LS-C98780
Rabbit Polyclonal to Human SENP1
Human
WB
Unconjugated
400µl  $305.00
Western blot of hSENP1-K578 in HL-60, HeLa cell line lysates (35 ug/lane). SENP1 (arrow) was detected using the purified antibody.
Western blot of hSENP1-K578 in HL-60, HeLa cell line lysates (35 ug/lane). SENP1 (arrow) was detected using the purified antibody.

SENP1 Antibody LS-C502018
Rabbit Polyclonal (IgG) to Human SENP1
Mouse, Human
ELISA IF IHC WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human colon cancer using SENP1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using SENP1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human colon cancer using SENP1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using SENP1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

SENP1 Antibody (C-Terminus) IHC-plus™ LS-B5861
Rabbit Polyclonal (IgG) to Human SENP1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human
IHC IHC-P WB
Unconjugated
50µg  $485.00
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SENP1 Antibody (C-Terminus, HRP) LS-C459648
Rabbit Polyclonal (IgG) to Human SENP1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC IHC-P WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SENP1 Antibody (C-Terminus, Biotin) LS-C459646
Rabbit Polyclonal (IgG) to Human SENP1
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC IHC-P WB
Biotin Conjugated
100µl 1mg/ml  $385.00
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SENP1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SENP1 antibody Western blot of HepG2 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SENP1 Antibody LS-C403527
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human liver cancer using SENP1 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:35.
Immunohistochemistry of Human liver cancer using SENP1 Polyclonal Antibody at dilution of 1:35.

SENP1 Antibody LS-C402952
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human gastric cancer using SENP1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human gastric cancer using SENP1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:40.

SENP1 Antibody LS-C406184
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human liver cancer using SENP1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human liver cancer using SENP1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human thyroid cancer using SENP1 Polyclonal Antibody at dilution of 1:25.

SENP1 Antibody LS-C754081
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Unconjugated
100µg  $375.00

SENP1 Antibody (aa28-59) LS-C328614
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

SENP1 Antibody (aa28-59, Biotin) LS-C245736
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

SENP1 Antibody (aa28-59, FITC) LS-C245738
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

SENP1 Antibody (aa28-59, AP) LS-C245735
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

SENP1 Antibody (aa28-59, APC) LS-C245737
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

SENP1 Antibody (aa28-59, PE) LS-C245739
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

SENP1 Antibody (aa28-59, Azide-free, HRP) LS-C247845
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

SENP1 Antibody (1-80 aa, N-terminal) LS-C386008
Rabbit Polyclonal (IgG) to Human SENP1
Mouse, Human
ELISA IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of SENP1 antibody
Western blot of SENP1 antibody

SENP1 Antibody (Asp2) LS-C176345
Rabbit Polyclonal to Human SENP1
Mouse, Human
IHC IHC-P WB
Unconjugated
100µl  $345.00
IHC of SENP1 (D2) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of SENP1 (D2) pAb in extracts from Jurkat cells.
IHC of SENP1 (D2) pAb in paraffin-embedded human breast carcinoma tissue.
Western blot of SENP1 (D2) pAb in extracts from Jurkat cells.

SENP1 Antibody (N-Terminus) LS-C353417
Rabbit Polyclonal to Human SENP1
Dog, Bovine, Human, Monkey
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of SENP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of SENP1 expression in Jurkat (A); HL60 (B) whole cell lysates.
Immunohistochemical analysis of SENP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Western blot analysis of SENP1 expression in Jurkat (A); HL60 (B) whole cell lysates.

SENP1 Antibody (clone 1D7) LS-C175077
Mouse Monoclonal [clone 1D7] (IgG1) to Human SENP1
Human
Flo WB
Unconjugated
100µl 1mg/ml  $345.00
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP1.
HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SENP1 antibody, and then analyzed by flow cytometry.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SENP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SENP1.
HEK293T cells transfected with either overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SENP1 antibody, and then analyzed by flow cytometry.

SENP1 Antibody (aa262-289) LS-C324998
Rabbit Polyclonal (IgG) to Mouse SENP1
Mouse
ELISA WB
Unconjugated
200µl  $530.00

SENP1 Antibody LS-C408290
Rabbit Polyclonal (IgG) to Human SENP1
Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using SENP1 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Western blot analysis of extracts of various cell lines, using SENP1 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.

SENP1 Antibody (aa560-590) LS-C328615
Rabbit Polyclonal (IgG) to Human SENP1
Human
ELISA WB
Unconjugated
200µl  $530.00
Showing 1-25 of 47 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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