SEMA5A / Semaphorin 5A

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

SEMA5A / Semaphorin 5A (9)

Publications

No (9)

Tag

6His, C-terminus (2)

Fc (1)

GST, N-terminus (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

HEK 293 Cells (2)

Human Cells (4)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (5)

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SEMA5A / Semaphorin 5A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116971

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.57 kDa

Price:

100 µg/$710

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Human SEMA5A / Semaphorin 5A Protein (Recombinant GST, N-terminus) (aa393-499) - LS-G60963

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SEMA5A / Semaphorin 5A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68197

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

118.1 kDa

Price:

20 µg/$1,107

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Mouse SEMA5A / Semaphorin 5A Protein (Recombinant His) (Met1-Thr765) - LS-G98268

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.1 kDa

Price:

50 µg/$721

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Human SEMA5A / Semaphorin 5A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81641

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

120.57 kDa

Price:

20 µg/$215

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Human SEMA5A / Semaphorin 5A Protein (Recombinant Fc) (Met1-Thr765) - LS-G97871

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

110.7 kDa

Price:

50 µg/$721

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Human SEMA5A / Semaphorin 5A Protein (Recombinant His) (Met1-Met968) - LS-G97873

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

107 kDa

Price:

50 µg/$721

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Human SEMA5A / Semaphorin 5A Protein (Recombinant 6His, C-terminus) (Glu23-Thr765) - LS-G39005

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.71kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human SEMA5A / Semaphorin 5A Protein (Recombinant 6His, C-terminus) (Glu23-Thr765) - LS-G139696

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.7 kDa

Price:

10 µg/$288; 50 µg/$436

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