SEMA5A / Semaphorin 5A

sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

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ELISA Kits (5)

Type

Custom (3)

Sandwich (2)

Target

SEMA5A / Semaphorin 5A (5)

Reactivity

Human (4)

Mouse (1)

Format

96-Well Microplate (1)

96-Well Strip Plate (4)

Publications

No (5)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (2)

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Human SEMA5A / Semaphorin 5A (Sandwich ELISA) ELISA Kit - LS-F8175

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$902

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Human SEMA5A / Semaphorin 5A (Custom ELISA) ELISA Kit - LS-F50717

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$672

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Human SEMA5A / Semaphorin 5A (Custom ELISA) ELISA Kit - LS-F17876

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Mouse SEMA5A / Semaphorin 5A (Custom ELISA) ELISA Kit - LS-F17877

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human SEMA5A / Semaphorin 5A (Sandwich ELISA) ELISA Kit - LS-F33660

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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