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SEMA3E / Semaphorin 3E

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation.

Gene Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: SEMA3E, M-SEMAH, SEMAH, Semaphorin 3E, M-SemaK, Semaphorin-3E, Coll-5, KIAA0331
Target Sequences: AB002329 NP_036563.1 O15041

Publications (1)

1
Circulating Neurovascular Guidance Molecules and Their Relationship with Peripheral Microvascular Impairment in Systemic Sclerosis. Eloisa Romano, Irene Rosa, Bianca Saveria Fioretto, Marco Matucci-Cerinic, Mirko Manetti. Life (Basel, Switzerland). 2022 July;12: [Full Text Article] [PubMed:35888144] [PMC:PMC9316343]

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
SEMA3E / Semaphorin 3E (5)
No (5)
His (2)
His,N-terminus (1)
Myc-DDK (Flag) (2)
Chicken (1)
Human (2)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
SEMA3E / Semaphorin 3E Protein - Recombinant Semaphorin 3E By SDS-PAGE
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E. coli
His,N-terminus
59.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SEMA3E / Semaphorin 3E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
89 kDa
20 µg/$215
SEMA3E / Semaphorin 3E Protein - Recombinant Semaphorin 3E By SDS-PAGE
Select
E. coli
His
11.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
SEMA3E / Semaphorin 3E Protein - Recombinant Semaphorin 3E By SDS-PAGE
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E. coli
His
12.3 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
SEMA3E / Semaphorin 3E Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
89 kDa
100 µg/$710
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).