SELPLG / PSGL-1 / CD162

selectin P ligand

SELPLG / PSGL-1 / CD162 is a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

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Products

Proteins (10)

Type

Over-Expression Lysate (1)

Recombinant (9)

Target

SELPLG / PSGL-1 / CD162 (10)

Application

SDS-PAGE (1)

Publications

No (10)

Tag

6His, N-terminus (1)

Fc (1)

Fc, C-terminus (4)

His-Fc (1)

His-GST-S (1)

Human IgG1 Fc, C-terminus (1)

Myc-DDK (Flag) (1)

Species

Human (5)

Mouse (4)

Rat (1)

Source

E. coli (2)

HEK 293 Cells (2)

Human Cells (3)

Mammalian Cells (3)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (7)

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Human SELPLG / PSGL-1 / CD162 Protein (Recombinant Human IgG1 Fc, C-terminus) (Met1-Val295) - LS-G48544

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human PSGL-1/Fc is a disulfide-linked homodimer after removal of the signal peptide and the prppeptide. The reduced monomer consists of 526 amino acids and has a predicted molecular mass of 57.1 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh PSGL-1/Fc monomer is approximately 110-120 kDa due to glycosylation.

Price:

100 µg/$441

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Mouse SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc, C-terminus) (Gln42-Cys307) - LS-G39524

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54.7kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human SELPLG / PSGL-1 / CD162 Protein (Recombinant His-Fc) (Met1-Val295) - LS-G97801

Source:

Human Cells

Tag:

His-Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.1 kDa

Price:

100 µg/$721

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Mouse SELPLG / PSGL-1 / CD162 Protein (Recombinant His-GST-S) (aa94-345) - LS-G24178

Source:

E. coli

Tag:

His-GST-S

Molecular Weight:

56.2 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

Select

Human SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc, C-terminus) - LS-G137856

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,262; 1 mg/$1,627

Select

Human SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc, C-terminus) (Thr44-Gly295) - LS-G139336

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.7 kDa

Price:

10 µg/$277; 50 µg/$389

Select

Mouse SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc, C-terminus) (Gln42-Cys307) - LS-G139374

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54.7 kDa

Price:

10 µg/$281; 50 µg/$389

Select

Rat SELPLG / PSGL-1 / CD162 Protein (Recombinant 6His, N-terminus) - LS-G132718

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

32.3kDa

Price:

10 µg/$278; 50 µg/$422; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

Select

Mouse SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc) (Met1-Cys307) - LS-G98836

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

57.4 kDa

Price:

100 µg/$721

Select

Human SELPLG / PSGL-1 / CD162 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117616

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42 kDa

Price:

100 µg/$494

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