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SELP / P-Selectin / CD62P

selectin P (granule membrane protein 140kDa, antigen CD62)

SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene Name: selectin P (granule membrane protein 140kDa, antigen CD62)
Synonyms: SELP, CD62P, CD62, GMP-140, GMRP, Granule membrane protein 140, LECAM3, P-selectin, PSEL, CD62P antigen, GMP140, Granulocyte membrane protein, GRMP, PADGEM
Target Sequences: NM_003005 NP_002996.2

Publications (3)

1
Targeting P-selectin blocks neuroblastoma growth. Nolo R, Herbrich S, Rao A, Zweidler-McKay P, Kannan S, Gopalakrishnan V, ,. Oncotarget. 2017 8:86657-86670. (IP; Human) [Full Text Article] [PubMed:29156825] Related Antibodies: LS-B3656.
2
Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition. Neto-Neves EM, Brown MB, Zaretskaia MV, Rezania S, Goodwill AG, McCarthy BP, Persohn SA, Territo PR, Kline JA. The American journal of pathology. 2017 April;187:700-712. [Full Text Article] [PubMed:28183533] [PMC:PMC5397717]
3
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Marcus Ruscetti, John P Morris th, Riccardo Mezzadra, James Russell, Josef Leibold, Paul B Romesser, Janelle Simon, Amanda Kulick, Yu-Jui Ho, Myles Fennell, Jinyang Li, Robert J Norgard, John E Wilkinson, Direna Alonso-Curbelo, Ramya Sridharan, Daniel A Heller, Elisa de Stanchina, Ben Z Stanger, Charles J Sherr, Scott W Lowe. Cell. 2020 April;181:424-441.e21. [Full Text Article] [PubMed:32234521] [PMC:PMC7278897]

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ELISA Kits (44)
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SELP / P-Selectin / CD62P (44)
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SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$889
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$741
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.041 - 30 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
SELP / P-Selectin / CD62P ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Saliva, Serum, Tissue Homogenates, Urine
1 Plate/$925
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.8 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SELP / P-Selectin / CD62P ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Citrate Plasma, Serum
1 Plate/$795
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
SELP / P-Selectin / CD62P ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).