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Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
Gene Name: | SEH1-like (S. cerevisiae) |
Synonyms: | SEH1L, SEC13L, Seh1, SEH1A, SEH1B, Nucleoporin SEH1, Sec13 like protein, SEC13-like protein, SEH1-like (S. cerevisiae) |
Target Sequences: | NM_031216 NP_112493.2 Q96EE3 |
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