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Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins. Found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins.
Gene Name: | Sec61 alpha 2 subunit (S. cerevisiae) |
Family/Subfamily: | Transporter , General secretary pathway - Sec61 alpha |
Synonyms: | SEC61A2, Sec61 alpha form 2, Sec61 alpha-2 |
Target Sequences: | NM_018144 NP_060614.2 Q9H9S3 |
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