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SEC14L2
SEC14-like 2 (S. cerevisiae)
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
| Gene Name: | SEC14-like 2 (S. cerevisiae) |
| Synonyms: | SEC14L2, C22orf6, HTAP, KIAA1186, KIAA1658, SEC14 (S. cerevisiae)-like 2, SEC14-like protein 2, SPF, Squalene transfer protein, Supernatant protein factor, TAP, Tocopherol-associated protein, SEC14-like 2 (S. cerevisiae) |
| Target Sequences: | NM_012429 NP_036561.1 O76054 |
Publications (1)
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