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SDR9C1 / BDH1
3-hydroxybutyrate dehydrogenase, type 1
SDR9C1 / BDH1 encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
| Gene Name: | 3-hydroxybutyrate dehydrogenase, type 1 |
| Synonyms: | BDH1, BDH, SDR9C1 |
| Target Sequences: | BC005844 AAH05844.1 Q02338 |
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