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SDR / SDPR is a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.
Gene Name: | serum deprivation response |
Synonyms: | SDPR, Cavin-2, CAVIN2, PS-p68, SDR, Serum deprivation response |
Target Sequences: | NM_004657 NP_004648.1 O95810 |
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