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B001/B101
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20700 44th Avenue W
Lynnwood, WA 98036
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SDHAF2
succinate dehydrogenase complex assembly factor 2
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
| Gene Name: | succinate dehydrogenase complex assembly factor 2 |
| Synonyms: | SDHAF2, PGL2, SDH assembly factor 2, SDH5, C11orf79, HSDH5 |
| Target Sequences: | NM_017841 NP_060311.1 Q9NX18 |
Publications (1)
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