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SDCBP2 / Syntenin 2
syndecan binding protein (syntenin) 2
The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031.
| Gene Name: | syndecan binding protein (syntenin) 2 |
| Synonyms: | SDCBP2, SITAC, Syndecan-binding protein 2, ST-2, Syntenin-2, SITAC18 |
| Target Sequences: | NM_015685 NP_056500.2 Q9H190 |
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