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SDC2 / Syndecan 2

syndecan 2

SDC2 / Syndecan 2 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Gene Name: syndecan 2
Synonyms: SDC2, CD362, CD362 antigen, HSPG, HSPG1, Fibroglycan, Syndecan proteoglycan 2, SYND2, Syndecan 2, Syndecan-2
Target Sequences: J04621 AAA52701.1 P34741

Publications (3)

1
Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Multhaupt H, Couchman JR. Molecular cancer. Jan;14:15. [Full Text Article] [PubMed:25623282] [PMC:PMC4326193] Related Antibodies: LS-B2981.
2
Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. Waters AM, Stafman LL, Garner EF, Mruthyunjayappa S, Stewart JE, Friedman GK, Coleman JM, Markert JM, Gillespie GY, Beierle EA. Translational oncology. 2016 9:419-430. (WB; Human) [Full Text Article] [PubMed:27751346] [PMC:PMC5067929] Related Antibodies: LS-B2981.
3
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165<sub>-dependent neovascularization. Corti F, Wang Y, Rhodes JM, Atri D, Archer-Hartmann S, Zhang J, Zhuang ZW, Chen D, Wang T, Wang Z, Azadi P, Simons M. Nature communications. 2019 April;10:1562. [Full Text Article] [PubMed:30952866] [PMC:PMC6450910] Related Antibodies: LS-B2981.

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Products
ELISA Kits (10)
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SDC2 / Syndecan 2 (10)
Human (3)
Mouse (2)
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12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (7)
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Serum (8)
Tissue Homogenates (3)
SDC2 / Syndecan 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
SDC2 / Syndecan 2 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SDC2 / Syndecan 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SDC2 / Syndecan 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
SDC2 / Syndecan 2 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SDC2 / Syndecan 2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$870
SDC2 / Syndecan 2 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
SDC2 / Syndecan 2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
SDC2 / Syndecan 2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SDC2 / Syndecan 2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).