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SDC2 / Syndecan 2

syndecan 2

SDC2 / Syndecan 2 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Gene Name: syndecan 2
Synonyms: SDC2, CD362, CD362 antigen, HSPG, HSPG1, Fibroglycan, Syndecan proteoglycan 2, SYND2, Syndecan 2, Syndecan-2
Target Sequences: J04621 AAA52701.1 P34741

Publications (3)

1
Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Multhaupt H, Couchman JR. Molecular cancer. Jan;14:15. [Full Text Article] [PubMed:25623282] [PMC:PMC4326193] Related Antibodies: LS-B2981.
2
Effect of Repeat Dosing of Engineered Oncolytic Herpes Simplex Virus on Preclinical Models of Rhabdomyosarcoma. Waters AM, Stafman LL, Garner EF, Mruthyunjayappa S, Stewart JE, Friedman GK, Coleman JM, Markert JM, Gillespie GY, Beierle EA. Translational oncology. 2016 9:419-430. (WB; Human) [Full Text Article] [PubMed:27751346] [PMC:PMC5067929] Related Antibodies: LS-B2981.
3
N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165<sub>-dependent neovascularization. Corti F, Wang Y, Rhodes JM, Atri D, Archer-Hartmann S, Zhang J, Zhuang ZW, Chen D, Wang T, Wang Z, Azadi P, Simons M. Nature communications. 2019 April;10:1562. [Full Text Article] [PubMed:30952866] [PMC:PMC6450910] Related Antibodies: LS-B2981.

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Products
Antibodies (21)
Primary (21)
SDC2 / Syndecan 2 (21)
Human (20)
Mouse (5)
Rat (5)
Monkey (1)
IHC (8)
IHC-P (7)
WB (17)
Flo (1)
ELISA (10)
ICC (1)
IF (2)
Peptide-ELISA (3)
rabbit (18)
mouse (1)
rat (2)
Product Group
IHCPlus (3)
IgG (15)
IgG2a (1)
IgG2a,k (1)
IgG2b (1)
monoclonal mc (3)
polyclonal pc (18)
1B2 (1)
305507 (1)
305515 (1)
APC Conjugated (2)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (15)
50-130 aa, Internal (1)
Internal (1)
aa19-144 (1)
aa65-114 (1)
aa81-130 (1)
No (20)
Yes (1)
SDC2 / Syndecan 2 Antibody - Anti-SDC2 / Syndecan 2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$1,017
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$1,017
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$1,017
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$1,017
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$1,017
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SDC2 / Syndecan 2 Rat anti-Human Monoclonal (APC) (305515) Antibody
Human
Flo
APC Conjugated
100 Tests/$930
SDC2 / Syndecan 2 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
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SDC2 / Syndecan 2 Rat anti-Human Monoclonal (aa19-144) (305507) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$896
SDC2 / Syndecan 2 Antibody - Anti-SDC2 / Syndecan 2 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (aa65-114) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
SDC2 / Syndecan 2 Antibody - Western blot of extracts of various cell lines, using SDC2 antibody.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
SDC2 / Syndecan 2 Antibody - Detection limit for recombinant GST tagged SDC2 is 1 ng/ml as a capture antibody.
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SDC2 / Syndecan 2 Mouse anti-Human Monoclonal (1B2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
SDC2 / Syndecan 2 Antibody
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SDC2 / Syndecan 2 Antibody - 1:100 staining human pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SDC2 / Syndecan 2 Antibody - Immunochemical staining of human SDC2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P
Unconjugated
100 µl/$412
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SDC2 / Syndecan 2 Antibody - Western blot analysis of extracts of various cell lines, using SDC2 Antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SDC2 / Syndecan 2 Antibody - Western blot analysis of Syndecan 2 expression in COS7 (A), MCF7 (B), CT26 (C), PC12 (D) whole cell lysates.
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SDC2 / Syndecan 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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SDC2 / Syndecan 2 Rabbit anti-Rat Polyclonal (Preservative Free) Antibody
Rat
IHC-P
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-21 of 21 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).