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SCYL1 / NTKL
SCY1-like 1 (S. cerevisiae)
SCYL1 / NTKL is a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | SCY1-like 1 (S. cerevisiae) |
| Family/Subfamily: | Protein Kinase , SCY1 |
| Synonyms: | SCYL1, CVAK90, GKLP, HT019, N-terminal kinase-like, p105, SCY1-like 1 (S. cerevisiae), SCY1-like protein 1, N-terminal kinase-like protein, NKTL, NTKL, TAPK, TEIF |
| Target Sequences: | NM_020680 NP_065731.3 Q96KG9 |
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