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Scramblase / PLSCR1
phospholipid scramblase 1
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
| Gene Name: | phospholipid scramblase 1 |
| Synonyms: | PLSCR1, Phospholipid scramblase 1, PL scramblase 1, Scramblase, MMTRA1B |
| Target Sequences: | NM_021105 NP_066928.1 O15162 |
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