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SCIN

scinderin

Ca2+-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes.

Gene Name: scinderin
Synonyms: SCIN, Adseverin, KIAA1905, Scinderin
Target Sequences: NM_001112706 NP_001106177.1 Q9Y6U3

Publications (1)

1
Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides. Michel Neidhart, Agnieszka Pajak, Katerina Laskari, Niels P Riksen , Leo A B Joosten , Mihai G Netea , Esther Lutgens , Eric S G Stroes, Adrian Ciurea, Oliver Distler, Mariam Grigorian, Emmanuel Karouzakis. Frontiers in immunology. 2019 Apr;10:791. [Full Text Article] [PubMed:31037071] [PMC:PMC6476283] Related Antibodies: LS-C499726.

☰ Filters
Antibodies (6)
Proteins (4)
Over-Expression Lysate (2)
Primary (6)
Recombinant (2)
SCIN (10)
Human (6)
Mouse (1)
IHC (1)
WB (3)
ELISA (5)
ICC (1)
IF (2)
IP (1)
rabbit (6)
IgG (6)
polyclonal pc (6)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (3)
aa281-585 (1)
No (9)
Yes (1)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
SCIN Antibody - Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using SCIN antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.
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SCIN Rabbit anti-Human Polyclonal (aa281-585) Antibody
Human
ICC, WB
Unconjugated
100 µl/$450
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SCIN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
SCIN Antibody - Immunofluorescent analysis of HepG2 cells using SCIN Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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SCIN Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
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SCIN Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SCIN Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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SCIN Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SCIN Protein - Purified recombinant protein SCIN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52.6 kDa
20 µg/$1,107
SCIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.6 kDa
20 µg/$150
SCIN Protein - 12.5% SDS-PAGE of human SCIN stained with Coomassie Blue
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Wheat Germ Extract
GST
79.2 kDa
10 µg/$479; 25 µg/$670
SCIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.6 kDa
100 µg/$494
Viewing 1-10 of 10 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).