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SCG2 / Secretogranin II

secretogranin II

SCG2 / Secretogranin II is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

Gene Name: secretogranin II
Synonyms: SCG2, Chromogranin-C, CHGC, EM66, Secretogranin II, Secretoneurin, SN, Secretogranin-2, SGII
Target Sequences: NM_003469 NP_003460.2 P13521

Publications (1)

1
Longitudinal CSF proteomics identifies NPTX2 as a prognostic biomarker of Alzheimer's disease. Ondrej Libiger, Leslie M Shaw, Mark H Watson, Angus C Nairn, Kelly L Umaña, Michael C Biarnes, Rosa M Canet-Avilés, Clifford R Jack Jr, Yannick-André Breton, Laetitia Cortes, Daniel Chelsky, Daniel S Spellman, Susan A Baker, Nandini Raghavan, William Z Potter, Alzheimer's Disease Neuroimaging Initiative (ADNI); Foundation for the National Institutes of Health (FNIH) Biomarkers Consortium, Longitudinal CSF Proteomics Project Team. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021 December;17:1976-1987. [Full Text Article] [PubMed:33984181] [PMC:PMC9222372]

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Antibodies (66)
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SCG2 / Secretogranin II Antibody - Anti-SCG2 / Secretogranin II antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
SCG2 / Secretogranin II Antibody - Immunofluorescence analysis of MCF-7 cells.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SCG2 / Secretogranin II ELISA Kit
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Sandwich
96-Well Microplate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
SCG2 / Secretogranin II ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
SCG2 / Secretogranin II Protein - Recombinant  Secretogranin II By SDS-PAGE
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E. coli
His, N-Terminal
71.51 kDa
10 µg/$285; 50 µg/$467; 100 µg/$747; 200 µg/$932; 1 mg/$2,058; 500 µg/$1,590; 5 mg/$3,263; 2 mg/$2,246
SCG2 / Secretogranin II Protein
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HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human SCG2 comprises 612 amino acids and has a predicted molecular mass of 70.5 kDa.
100 µg/$441
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IHC, IP, WB
Unconjugated
200 µl/$558
SCG2 / Secretogranin II Antibody - SCG2 antibody (0.3 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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SCG2 / Secretogranin II Goat anti-Human Polyclonal (aa203-217) Antibody
Rabbit, Pig, Horse, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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SCG2 / Secretogranin II Mouse anti-Human Monoclonal (6B7) Antibody
Human
ELISA
Unconjugated
100 µg/$423
SCG2 / Secretogranin II Antibody - Western blot of SCG2 / Secretogranin II antibody.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa31-617) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
SCG2 / Secretogranin II Antibody - Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
SCG2 / Secretogranin II Antibody - Anti-SCG2 / Secretogranin II antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa272-542) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
SCG2 / Secretogranin II Antibody - Immunofluorescent analysis of Secretogranin-2 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
SCG2 / Secretogranin II Antibody - Immunohistochemical staining of paraffin-embedded Human adult brain tissue within the normal limits using anti-SCG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:500)
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SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31) (OTI3F12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SCG2 / Secretogranin II Rabbit anti-Rat Polyclonal Antibody
Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$860
SCG2 / Secretogranin II Antibody - Chromogranin-C Antibody IHC of formalin-fixed and paraffin-embedded mouse brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the Chromogranin-C Antibody for immunohistochemistry.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal (aa246-274) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SCG2 / Secretogranin II Antibody - Squirrel monkey pituitary gland, staining visualized with Texas Red-labeled goat anti-rabbit antibody.
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SCG2 / Secretogranin II Rabbit anti-Human Polyclonal Antibody
Rat, Squirrel monkey, Human
IHC, WB
Unconjugated
100 µg/$572
SCG2 / Secretogranin II Antibody - Western blot of recombinant SCG2 / Secretogranin II.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa430-586) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SCG2 / Secretogranin II Antibody - Western blot of recombinant SCG2 / Secretogranin II.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa342-609) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571
SCG2 / Secretogranin II Antibody - Western blot of recombinant SCG2 / Secretogranin II.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SCG2 / Secretogranin II Rabbit anti-Mouse Polyclonal (aa11-187) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
SCG2 / Secretogranin II Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SCG2. (Right lane) cDNA for 48 hrs and lysed
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SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31-617) (OTI2B2) Antibody
Human
WB
Unconjugated
100 µl/$434
SCG2 / Secretogranin II Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY SCG2. (Right lane) cDNA for 48 hrs and lysed
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SCG2 / Secretogranin II Mouse anti-Human Monoclonal (aa31-617) (OTI8A3) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 93 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).