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SBDS

Shwachman-Bodian-Diamond syndrome

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Gene Name: Shwachman-Bodian-Diamond syndrome
Synonyms: SBDS, CGI-97, SWDS
Target Sequences: NM_016038 NP_057122.2 Q9Y3A5

Filtered By: None
Target
sbds (16)
Reactivity
Human (15)
Mouse (6)
Rat (5)
Bat (8)
Bovine (4)
Chimpanzee (6)
Dog (8)
Gibbon (6)
Guinea pig (4)
Horse (8)
Orangutan (6)
Pig (8)
Zebrafish (8)
Application
IHC (11)
IHC-P (5)
WB (12)
ELISA (1)
ICC (1)
IF (2)
IP (1)
Host
rabbit (15)
mouse (1)
Isotype
IgG (13)
IgG2b,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (15)
Clone
AT1E8 (1)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (7)
Epitope
C-Terminus (4)
aa51-100 (4)
Publications
No (16)
Showing 1-16 out of 16 results
SBDS Antibody (C-Terminus) LS-C40532
SBDS antibody LS-C40532 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Pig, Horse, Bat, Dog, Human
IHC WB
Unconjugated
SBDS Antibody (C-Terminus, HRP) LS-C447526
SBDS antibody LS-C40532 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Dog, Pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
IHC WB
HRP Conjugated
SBDS Antibody (C-Terminus, Biotin) LS-C448009
SBDS antibody LS-C40532 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Dog, Pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
IHC WB
Biotin Conjugated
SBDS Antibody (C-Terminus, FITC) LS-C447525
SBDS antibody LS-C40532 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Dog, Pig, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
IHC WB
FITC Conjugated
SBDS Antibody LS-C668568
Immunohistochemistry - Paraffin Image
Immunofluorescence Image

Rabbit Polyclonal to Human SBDS
Human
ICC IF IHC WB
Unconjugated
SBDS Antibody LS-C334358
Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
Immunofluorescence analysis of MCF7 cells.

Rabbit Polyclonal (IgG) to Human SBDS
Mouse, Rat, Human
IF IHC WB
Unconjugated
SBDS Antibody LS-C489106

Rabbit Polyclonal to Mouse SBDS
Mouse
IHC IHC-P IP WB
Unconjugated
SBDS Antibody (aa51-100) LS-C40531
SBDS antibody LS-C40531 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SBDS antibody LS-C40531 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Bovine, Rat, Human
IHC IHC-P WB
Unconjugated
SBDS Antibody (aa51-100, HRP) LS-C448008
SBDS antibody LS-C40531 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SBDS antibody LS-C40531 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Orangutan, Chimpanzee
IHC IHC-P WB
HRP Conjugated
SBDS Antibody (aa51-100, Biotin) LS-C448006
SBDS antibody LS-C40531 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SBDS antibody LS-C40531 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Orangutan, Chimpanzee
IHC IHC-P WB
Biotin Conjugated
SBDS Antibody (aa51-100, FITC) LS-C448007
SBDS antibody LS-C40531 IHC of formalin-fixed, paraffin-embedded human Kidney. Positive label: Epithelial cells of renal tubule indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
SBDS antibody LS-C40531 Western blot of Jurkat lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Human SBDS
Zebrafish, Pig, Horse, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Orangutan, Chimpanzee
IHC IHC-P WB
FITC Conjugated
SBDS Antibody (clone AT1E8) LS-C175816
Western Blot: The cell lysates of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SBDS antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Mouse Monoclonal [clone AT1E8] (IgG2b,k) to Human SBDS
Human
ELISA WB
Unconjugated
SBDS Antibody LS-C673058
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

Rabbit Polyclonal (IgG) to Human SBDS
Human
Unconjugated
SBDS Antibody (HRP) LS-C673059

Rabbit Polyclonal (IgG) to Human SBDS
Human
HRP Conjugated
SBDS Antibody (Biotin) LS-C673062

Rabbit Polyclonal (IgG) to Human SBDS
Human
Biotin Conjugated
SBDS Antibody (FITC) LS-C673060

Rabbit Polyclonal (IgG) to Human SBDS
Human
FITC Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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