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SART1

squamous cell carcinoma antigen recognized by T cells

SART1 is two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

Gene Name: squamous cell carcinoma antigen recognized by T cells
Synonyms: SART1, Ara1, Allergen Hom s 1, HOMS1, HSnu66, IgE autoantigen, SART-1, Snu66, SNRNP110, SNU66 homolog, SART1(800) protein, SART1259, HSART-1, SART1(259) protein
Target Sequences: NM_005146 NP_005137.1 O43290

☰ Filters
Antibodies (11)
Proteins (4)
Over-Expression Lysate (2)
Primary (11)
Recombinant (2)
SART1 (15)
Human (11)
Mouse (5)
Rat (5)
Bat (1)
Bovine (1)
Monkey (1)
Pig (1)
Rabbit (1)
IHC (2)
IHC-P (1)
WB (10)
ELISA (2)
ICC (1)
IF (1)
IP (2)
Peptide-ELISA (2)
rabbit (10)
goat (1)
IgG (7)
polyclonal pc (11)
Unconjugated (11)
aa137-447 (1)
aa2-14 (1)
aa533-792 (1)
aa675-725 (1)
aa750-800 (1)
No (15)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
SART1 Antibody - Antibody (0.03 ug/ml) staining of Hela lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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SART1 Goat anti-Human Polyclonal (aa2-14) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
SART1 Antibody - IHC of paraffin-embedded Cal27 xenograft using SART1 antibody at 1:500 dilution.
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SART1 Rabbit anti-Human Polyclonal (aa137-447) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
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SART1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$351
SART1 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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SART1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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SART1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SART1 Antibody - Western blot analysis of extracts of various cell lines.
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SART1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
SART1 Rabbit anti-Human Polyclonal (aa750-800) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
SART1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$386
SART1 Antibody
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SART1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
SART1 Antibody - Sample (30 ug of whole cell lysate). A: H1299, B: Hela, C: Molt-4 . 7.5% SDS PAGE. SART1 antibody diluted at 1:5000.
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SART1 Rabbit anti-Human Polyclonal (aa533-792) Antibody
Human
WB
Unconjugated
100 µl/$450
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SART1 Rabbit anti-Human Polyclonal (aa675-725) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
SART1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SART1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
90.7 kDa
20 µg/$150
SART1 Protein - 12.5% SDS-PAGE of human SART1 stained with Coomassie Blue
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Wheat Germ Extract
GST
116.7 kDa
2 µg/$439
SART1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
90.7 kDa
100 µg/$494
Viewing 1-15 of 15 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).